Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259536 | 0.77 | DRD3 (0.44) | DRD2DRD3CYP2D6GRIN1GRIN2B | |
| SCHEMBL14490659 | 0.77 | DRD3 (0.44) | DRD2DRD3CYP2D6GRIN1GRIN2B | |
| SCHEMBL14490658 | 0.77 | DRD3 (0.44) | DRD2DRD3CYP2D6GRIN1GRIN2B | |
| SCHEMBL24399967 | 0.73 | DRD2 (0.41) | DRD2DRD3CYP2D6GRIN1GRIN2B | |
| SCHEMBL13998639 | 0.73 | DRD3 (0.44) | DRD2DRD3CYP2D6GRIN1GRIN2B | |
| SCHEMBL3498480 | 0.73 | DRD3 (0.44) | DRD2DRD3CYP2D6GRIN1GRIN2B | |
| SCHEMBL13998641 | 0.73 | DRD3 (0.44) | DRD2DRD3CYP2D6GRIN1GRIN2B | |
| SCHEMBL8267166 | 0.73 | DRD2 (0.55) | DRD2DRD3CYP2D6GRIN1GRIN2B | |
| SCHEMBL12891728 | 0.73 | DRD2 (0.55) | DRD2DRD3CYP2D6GRIN1GRIN2B | |
| SCHEMBL12891737 | 0.73 | DRD2 (0.44) | DRD2DRD3CYP2D6GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124654-A1 | Aryl and Heteroaryl Compounds, Compositions, Methods of Use | TRANSTECH PHARMA, INC. | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124654-A1 | Aryl and Heteroaryl Compounds, Compositions, Methods of Use | F3, F12, CFH | DRD2 2398/4885DRD3 1080/4885CYP2D6 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.