Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.97 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24400970 | 0.74 | MAPT (0.57) | MAPTKDM4EESR2ALDH1A1HPGD | |
| SCHEMBL6868397 | 0.72 | CYP1A2 (0.61) | MAPTKDM4EESR2ALDH1A1HSD17B10 | |
| SCHEMBL13115768 | 0.72 | CYP1A2 (0.61) | MAPTKDM4EESR2ALDH1A1HSD17B10 | |
| SCHEMBL701930 | 0.72 | CYP1A2 (0.61) | MAPTKDM4EESR2ALDH1A1HSD17B10 | |
| SCHEMBL8748295 | 0.71 | MAPT (0.53) | MAPTKDM4EESR2ALDH1A1HSD17B10 | |
| SCHEMBL3384639 | 0.71 | CYP1A2 (0.59) | MAPTKDM4EESR2ALDH1A1HSD17B10 | |
| SCHEMBL6937040 | 0.71 | CYP1A2 (0.59) | MAPTKDM4EESR2ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL13268932 | 0.71 | CYP1A2 (0.59) | MAPTKDM4EESR2ALDH1A1HSD17B10 | |
| SCHEMBL3734984 | 0.70 | CYP1A2 (0.58) | MAPTKDM4EESR2ALDH1A1HSD17B10 | |
| SCHEMBL3735109 | 0.70 | CYP1A2 (0.58) | MAPTKDM4EESR2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | BCL2, BAX, BAD | MAPT 3866/4885KDM4E 3373/4885ESR2 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.