SCHEMBL24400970

SCHEMBL24400970

COc1ccc(CCc2ccc(C)o2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ESR2 Q92731 1/20 0.57
HPGD P15428 1/20 0.49
TAAR1 Q96RJ0 1/20 0.48
TUBB4A P04350 1/20 0.46
TUBB P07437 1/20 0.46
TUBA3C P0DPH7 1/20 0.46
TUBA1B P68363 1/20 0.46
TUBA4A P68366 1/20 0.46
TUBB4B P68371 1/20 0.46
TUBB3 Q13509 1/20 0.46
TUBB2A Q13885 1/20 0.46
TUBB8 Q3ZCM7 1/20 0.46
TUBA3E Q6PEY2 1/20 0.46
TUBA1A Q71U36 1/20 0.46
TUBA1C Q9BQE3 1/20 0.46
TUBB6 Q9BUF5 1/20 0.46
TUBB2B Q9BVA1 1/20 0.46
TUBB1 Q9H4B7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4504077 0.84 ALDH1A1 (0.54) MAPTKDM4EESR2HPGDIDO1
SCHEMBL19258615 0.81 CHRM2 (0.45) MAPTTAAR1IDO1ALDH1A1
SCHEMBL4257456 0.78 KMT2A (0.62) MAPTKDM4EHPGDNPC1RAB9A
SCHEMBL834551 0.78 TAAR1 (0.73) TAAR1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL4249429 0.77 HTT (0.63) MAPTNPC1RAB9AF2RL1ALDH1A1
SCHEMBL12649436 0.74 PTPN1 (0.59) TAAR1CALM1ALDH1A1
SCHEMBL13856435 0.74 MAPT (0.97) MAPTKDM4EESR2HPGDAOC3
SCHEMBL13038170 0.74 ACHE (0.71) MAPTTAAR1TUBB4ATUBBTUBA3C
SCHEMBL8632136 0.72 ALDH1A1 (0.49) MAPTKDM4EESR2HPGDNPC1
SCHEMBL8748446 0.72 MAPT (0.52) MAPTKDM4EESR2HPGDTUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220137506-A1 PHOTORESIST COMPOSITIONS AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-05-05 US disclosed