Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 5/20 | 0.55 |
| ▸ | CCR8 | P51685 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775891 | 0.89 | SLC2A1 (0.53) | SLC2A1CCR8KCNH2HRH1HRH4 | |
| SCHEMBL4269307 | 0.80 | SLC2A1 (0.77) | SLC2A1CCR8KCNH2 | |
| SCHEMBL27577361 | 0.80 | SLC2A1 (0.77) | SLC2A1CCR8KCNH2 | |
| SCHEMBL13857011 | 0.79 | KCNH2 (0.47) | SLC2A1KCNH2MTNR1BPOLBKDR | |
| SCHEMBL4282967 | 0.77 | KDM4E (0.48) | KCNH2MTNR1BPOLBKDR | |
| SCHEMBL4268442 | 0.74 | ATM (0.48) | SLC2A1KCNH2MTNR1B | |
| SCHEMBL13857005 | 0.73 | SLC2A1 (0.55) | SLC2A1KCNH2 | |
| SCHEMBL13857009 | 0.72 | SLC2A1 (0.65) | SLC2A1KCNH2 | |
| SCHEMBL4273993 | 0.72 | SSTR3 (0.55) | — | |
| SCHEMBL13857004 | 0.71 | SLC2A1 (0.71) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534793-B2 | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | SMITHKLINE BEECHAM P.L.C. (GB) | 2009-05-19 | — | — | US | disclosed |
| US-7534793-B2 | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | SMITHKLINE BEECHAM P.L.C. (GB) | 2009-05-19 | — | — | US | disclosed |