Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.59 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CXCR6 | O00574 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13856379 | 0.75 | KMT2A (0.98) | KMT2AMEN1RAB9AALDH1A1KDM4E | |
| SCHEMBL3415947 | 0.75 | KMT2A (0.98) | KMT2AMEN1RAB9AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL2114038 | 0.74 | KMT2A (1.00) | KMT2AMEN1RAB9AALDH1A1KDM4E | |
| SCHEMBL3478681 | 0.72 | KMT2A (0.74) | KMT2AMEN1RAB9AALDH1A1KDM4E | |
| SCHEMBL13257640 | 0.70 | NPC1 (0.61) | KMT2AMEN1RAB9AALDH1A1POLB | |
| SCHEMBL13257856 | 0.70 | NPC1 (0.61) | KMT2AMEN1RAB9AALDH1A1POLB | |
| SCHEMBL5226157 | 0.68 | NPC1 (1.00) | KMT2AMEN1RAB9AALDH1A1KDM4E | |
| SCHEMBL381132 | 0.68 | TAS1R3 (0.68) | KMT2AMEN1RAB9AALDH1A1KDM4E | |
| SCHEMBL30098882 | 0.68 | TAS1R3 (0.68) | KMT2AMEN1RAB9AALDH1A1KDM4E | |
| SCHEMBL14290618 | 0.67 | CCR3 (0.47) | KMT2AMEN1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | BCL2, BAX, BAD | KMT2A 4047/4885MEN1 4323/4885RAB9A 3519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.