SCHEMBL138572

SCHEMBL138572

C1CNCCSC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12882833 1.00 CXCR4 (0.41)
SCHEMBL12100700 1.00
Hydrochloric Acid SCHEMBL1870653 0.97
SCHEMBL15355221 0.97 CXCR4 (0.47)
SCHEMBL624731 0.93
SCHEMBL869844 0.90
SCHEMBL17119216 0.90 CXCR4 (0.47)
SCHEMBL29016828 0.90 ALDH1A1 (0.53)
Thiomorpholine SCHEMBL6624599 0.90 ALDH1A1 (0.53)
Hydrochloric Acid SCHEMBL18396734 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1590 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340548-A1 KRAS G12C INHIBITORS FRONTIER MEDICINES CORP (US) 2025-11-06 US claimed
EP-4547666-A1 METHODS FOR TREATMENT OF CANCER Frontier Medicines Corporation (US) 2025-05-07 EP claimed
US-12221431-B2 Heterocyclic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-02-11 US claimed
EP-4426695-A1 KRAS G12C INHIBITORS Frontier Medicines Corporation (US) 2024-09-11 EP claimed
US-20240294536-A1 FUSED TRIAZOLO-PYRIMIDINE COMPOUNDS HAVING USEFUL PHARMACEUTICAL APPLICATION PIKSCI INC. (CA) 2024-09-05 US claimed
US-11987583-B2 Fused triazolo-pyrimidine compounds having useful pharmaceutical application PIKSCI INC. (CA) 2024-05-21 US claimed
US-20240150312-A1 PYRAZINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-05-09 US claimed
WO-2024006445-A1 METHODS FOR TREATMENT OF CANCER FRONTIER MEDICINES CORPORATION (US) 2024-01-04 WO claimed
CN-116444408-B Multi-target-point disulfiram derivative, pharmaceutical composition and antitumor application thereof 山东大学 2023-09-26 CN claimed
CN-116444408-A Multi-target-point disulfiram derivative, pharmaceutical composition and antitumor application thereof 山东大学 2023-07-18 CN claimed
EP-3252042-A1 BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL Sumitomo Chemical Company, Limited (JP) 2017-12-06 EP claimed
EP-3252041-A1 BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL Sumitomo Chemical Company, Limited (JP) 2017-12-06 EP claimed
US-20160024121-A1 BETA-LACTAMASE INHIBITORS VenatoRx Pharmaceuticals, Inc. 2016-01-28 US claimed
EP-2838534-A2 SUBSTITUTED BENZAMIDES AND THEIR USES The Board of Trustees of The Leland Stanford Junior University (US) 2015-02-25 EP claimed
US-20140024649-A1 Substituted Benzamides and Their Uses AUCKLAND UNISERVICES LIMITED (NZ) 2014-01-23 US claimed
WO-2013155338-A2 SUBSTITUTED BENZAMIDES AND THEIR USES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2013-10-17 WO claimed
US-20130040981-A1 Pyridylvinylpyrazoloquinolines as PAR1 inhibitors SANOFI (FR) 2013-02-14 US claimed
US-8022208-B2 Benzene derivative or salt thereof ASTELLAS PHARMA INC. (JP) 2011-09-20 US claimed
US-20090054352-A1 BENZENE DERIVATIVE OR SALT THEREOF ASTELLAS PHARMA INC. (JP) 2009-02-26 US claimed
EP-1947086-A1 BENZENE DERIVATIVE OR SALT THEREOF Astellas Pharma Inc. (JP) 2008-07-23 EP claimed