⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20688883 | 0.68 | — | — | |
| SCHEMBL21245971 | 0.65 | — | — | |
| SCHEMBL21238678 | 0.65 | NPC1 (0.33) | — | |
| SCHEMBL20852997 | 0.61 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL11401166 | 0.56 | — | — | |
| SCHEMBL13810607 | 0.49 | — | — | |
| SCHEMBL14446955 | 0.47 | — | — | |
| SCHEMBL7930276 | 0.47 | — | — | |
| SCHEMBL5104888 | 0.46 | — | — | |
| SCHEMBL284316 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895587-B2 | Insecticidal compounds based on arylthioacetamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-25 | — | — | US | disclosed |
| US-20140107161-A1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-04-17 | — | — | US | disclosed |
| EP-2709983-A1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2014-03-26 | — | — | EP | disclosed |
| WO-2012156400-A1 | INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-11-22 | — | — | WO | disclosed |