⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12344265 | 0.68 | — | — | |
| SCHEMBL13859293 | 0.65 | — | — | |
| SCHEMBL20688883 | 0.65 | — | — | |
| SCHEMBL21238678 | 0.62 | NPC1 (0.33) | — | |
| SCHEMBL20852997 | 0.58 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL932881 | 0.55 | — | — | |
| SCHEMBL11401166 | 0.54 | — | — | |
| SCHEMBL2114337 | 0.47 | — | — | |
| SCHEMBL15053255 | 0.47 | — | — | |
| SCHEMBL347101 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562906-B2 | TYK2 inhibitors and uses thereof | Nimbus Lakshimi, Inc. (US) | 2020-02-18 | — | — | US | disclosed |
| US-20190241576-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-08-08 | — | — | US | disclosed |