SCHEMBL1385998

SCHEMBL1385998

CC1CN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC(=O)N1C(c1ccnc(N(C)C)n1)C1CCNCC1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.40
F2 P00734 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1385204 0.90 F10 (0.39) F10F2
SCHEMBL1386665 0.89 F10 (0.42) F10
SCHEMBL1385911 0.88 F10 (0.46) F10F2
SCHEMBL4396056 0.85 F10 (0.36) F10
SCHEMBL4390477 0.83 F10 (0.38) F10
SCHEMBL4390831 0.83 F10 (0.41) F10
SCHEMBL1386871 0.78 F10 (0.48) F10F2
SCHEMBL1386731 0.76 F10 (0.43) F10F2
SCHEMBL4392578 0.76 KCNH2 (0.35) F10
SCHEMBL1385070 0.76 F10 (0.44) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4829449-B2 2011-12-07 JP claimed
JP-2003508353-A 2003-03-04 JP claimed
EP-1208097-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS Aventis Pharmaceuticals Inc. (US) 2002-05-29 EP claimed
WO-2001007436-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2001-02-01 WO claimed
US-7612075-B2 Substituted oxoazaheterocyclyl compounds AVENTIS PHARMACEUTICALS INC. (US) 2009-11-03 US disclosed