Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396056 | 0.95 | F10 (0.36) | F10KCNH2KLK1 | |
| SCHEMBL4386121 | 0.90 | KCNH2 (0.40) | F10KCNH2 | |
| SCHEMBL1386921 | 0.87 | F10 (0.45) | F10KCNH2KLK1 | |
| SCHEMBL4390477 | 0.87 | F10 (0.38) | F10IDH1 | |
| SCHEMBL4392578 | 0.85 | KCNH2 (0.35) | F10KCNH2 | |
| SCHEMBL1385998 | 0.83 | F10 (0.40) | F10 | |
| SCHEMBL1387117 | 0.82 | F10 (0.39) | F10KCNH2KLK1 | |
| SCHEMBL4393350 | 0.78 | F10 (0.37) | F10KCNH2IDH1 | |
| SCHEMBL4936205 | 0.75 | F10 (0.48) | F10KCNH2KLK1 | |
| SCHEMBL1387128 | 0.74 | F10 (0.43) | F10IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |