Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029011 | 0.92 | ENPP2 (0.43) | ENPP2PHLPP2PTPN11MEN1ALDH1A1 | |
| SCHEMBL13286618 | 0.92 | ENPP2 (0.43) | ENPP2PHLPP2PTPN11MEN1ALDH1A1 | |
| SCHEMBL13615160 | 0.91 | ENPP2 (0.44) | ENPP2PHLPP2PTPN11MPLSENP2 | |
| SCHEMBL13860864 | 0.90 | PTPN11 (0.44) | ENPP2PHLPP2PTPN11MEN1ALDH1A1 | |
| SCHEMBL13860879 | 0.90 | PHLPP2 (0.47) | ENPP2PHLPP2PTPN11MEN1ALDH1A1 | |
| SCHEMBL13860890 | 0.89 | PHLPP2 (0.43) | ENPP2PHLPP2PTPN11MEN1ALDH1A1 | |
| SCHEMBL13860946 | 0.88 | ENPP2 (0.46) | ENPP2PHLPP2PTPN11MEN1ALDH1A1 | |
| SCHEMBL13615143 | 0.87 | ENPP2 (0.48) | ENPP2PHLPP2PTPN11MEN1ALDH1A1 | |
| SCHEMBL12568522 | 0.87 | PTPN11 (0.40) | ENPP2PHLPP2PTPN11MEN1ALDH1A1 | |
| SCHEMBL12568511 | 0.86 | ENPP2 (0.42) | ENPP2PHLPP2PTPN11MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527862-B2 | Dyes for anisotropic dye films, dye compositions for anisotropic dye films, anisotropic dye films and polarizing elements | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-05-05 | — | — | US | disclosed |