SCHEMBL13865196

SCHEMBL13865196

CC(C)c1coc(-c2nn(Cc3ccccc3F)c3ccccc23)n1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BUB1 O43683 18/20 0.46
CHRM1 P11229 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13865208 0.85 BUB1 (0.48) BUB1CHRM1
SCHEMBL13865197 0.84 CYP2D6 (0.55) CHRM1
SCHEMBL13865192 0.83 BUB1 (0.46) BUB1CHRM1
SCHEMBL13865195 0.83 BUB1 (0.46) BUB1CHRM1
SCHEMBL13865191 0.81 MEN1 (0.46) BUB1CHRM1
SCHEMBL13865193 0.80 BUB1 (0.45) BUB1CHRM1
SCHEMBL13865226 0.80 BUB1 (0.51) BUB1CHRM1
SCHEMBL13865212 0.78 BUB1 (0.43) BUB1CHRM1
SCHEMBL13865223 0.78 BUB1 (0.43) BUB1CHRM1
SCHEMBL13865217 0.77 BUB1 (0.43) BUB1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934311-B1 NEW HETEROCYCLYLMETHYL-SUBSTITUTED PYRAZOL DERIVATES BAYER HEALTHCARE AG (DE) 2009-05-13 EP disclosed