Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865394 | 0.98 | CA14 (0.48) | TDP1CA14MEN1KMT2AGAA | |
| SCHEMBL13327086 | 0.91 | TDP1 (0.47) | TDP1CA14MEN1KMT2AGAA | |
| SCHEMBL16349494 | 0.89 | TDP1 (0.47) | TDP1CA14MEN1KMT2AGAA | |
| SCHEMBL13327079 | 0.89 | TDP1 (0.60) | TDP1CA14MEN1KMT2AGAA | |
| SCHEMBL16349646 | 0.88 | CA14 (0.38) | TDP1CA14MEN1KMT2AGAA | |
| SCHEMBL13865393 | 0.88 | CA14 (0.47) | TDP1CA14MEN1KMT2AGAA | |
| SCHEMBL13327085 | 0.88 | TDP1 (0.46) | TDP1CA14MEN1KMT2AGAA | |
| SCHEMBL13327229 | 0.87 | CA14 (0.39) | TDP1CA14MEN1KMT2AGAA | |
| SCHEMBL16349524 | 0.87 | TDP1 (0.45) | TDP1CA14MEN1KMT2AGAA | |
| SCHEMBL16349495 | 0.87 | CA14 (0.50) | TDP1CA14MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531676-B2 | Lipids | CELLTECH R & D LIMITED (GB) | 2009-05-12 | — | — | US | disclosed |
| US-7531676-B2 | Lipids | CELLTECH R & D LIMITED (GB) | 2009-05-12 | — | — | US | disclosed |