Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865394 | 0.91 | CA14 (0.48) | CA14MEN1KMT2ATDP1CA12 | |
| SCHEMBL13865384 | 0.88 | TDP1 (0.45) | CA14MEN1KMT2ATDP1CA12 | |
| SCHEMBL16349495 | 0.80 | CA14 (0.50) | CA14MEN1KMT2ATDP1CA12 | |
| SCHEMBL13360044 | 0.80 | CA14 (0.43) | CA14TDP1CA12CA1CA2 | |
| SCHEMBL13327086 | 0.79 | TDP1 (0.47) | CA14MEN1KMT2ATDP1CA12 | |
| SCHEMBL13327079 | 0.79 | TDP1 (0.60) | CA14MEN1KMT2ATDP1CA12 | |
| SCHEMBL16349550 | 0.79 | TDP1 (0.57) | CA14MEN1KMT2ATDP1CA12 | |
| SCHEMBL9017295 | 0.78 | CA14 (0.59) | CA14MEN1KMT2ATDP1CA12 | |
| SCHEMBL13360023 | 0.78 | DNM1 (0.43) | CA14 | |
| SCHEMBL13868764 | 0.78 | DNM1 (0.43) | CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531676-B2 | Lipids | CELLTECH R & D LIMITED (GB) | 2009-05-12 | — | — | US | disclosed |
| US-7531676-B2 | Lipids | CELLTECH R & D LIMITED (GB) | 2009-05-12 | — | — | US | disclosed |