Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | HTR6 | P50406 | 13/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4476844 | 0.91 | PPARG (0.53) | PPARGPPARDPPARAHTR6 | |
| SCHEMBL3035930 | 0.82 | PPARG (0.67) | PPARGPPARDPPARAHTR6 | |
| SCHEMBL4478083 | 0.81 | PPARG (0.55) | PPARGPPARDPPARAHTR6ALDH1A1 | |
| SCHEMBL4487054 | 0.81 | PPARG (0.65) | PPARGPPARDPPARAHTR6 | |
| SCHEMBL4559260 | 0.77 | PPARG (0.54) | PPARGPPARDPPARAHTR6 | |
| SCHEMBL3035346 | 0.77 | PPARG (0.81) | PPARGPPARDPPARAHTR6 | |
| SCHEMBL3030224 | 0.76 | PPARG (0.54) | PPARGPPARDPPARAHTR6CYP3A4 | |
| SCHEMBL3020042 | 0.75 | PPARG (0.57) | PPARGPPARDPPARAHTR6 | |
| SCHEMBL3019374 | 0.74 | PPARG (0.49) | PPARGPPARDPPARAHTR6 | |
| SCHEMBL3019379 | 0.74 | PPARG (0.49) | PPARGPPARDPPARAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531568-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2009-05-12 | — | — | US | disclosed |
| US-7531568-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2009-05-12 | — | — | US | disclosed |