Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906791 | 0.87 | HDAC1 (0.37) | HDAC1HDAC2LMNASMN1; SMN2HPGD | |
| SCHEMBL9906799 | 0.84 | LMNA (0.36) | HDAC1HDAC2LMNASMN1; SMN2 | |
| SCHEMBL9906809 | 0.83 | HDAC1 (0.38) | HDAC1HDAC2LMNASMN1; SMN2GRM2 | |
| SCHEMBL20272385 | 0.80 | LMNA (0.44) | HDAC1HDAC2LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL9906788 | 0.80 | LMNA (0.43) | HDAC1HDAC2LMNASMN1; SMN2HPGD | |
| SCHEMBL18622527 | 0.78 | LMNA (0.44) | HDAC1HDAC2LMNASMN1; SMN2HPGD | |
| SCHEMBL17591250 | 0.78 | HDAC1 (0.34) | HDAC1HDAC2LMNASMN1; SMN2 | |
| SCHEMBL9906790 | 0.78 | LMNA (0.32) | HDAC1HDAC2LMNASMN1; SMN2 | |
| SCHEMBL9906800 | 0.77 | HDAC1 (0.38) | HDAC1HDAC2LMNASMN1; SMN2GRM2 | |
| SCHEMBL12695600 | 0.76 | HDAC1 (0.35) | HDAC1HDAC2LMNASMN1; SMN2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105427-A1 | Cleavable Block Copolymers, Functionalized Nanoporous Thin Films and Related Methods of Preparation | UNIVERSITY OF MASSACHUSETTS | 2009-04-23 | — | — | US | disclosed |