Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3886671 | 0.92 | DPP4 (0.54) | DPP4KMT2AMAPK1LMNAMEN1 | |
| SCHEMBL13866870 | 0.85 | DPP4 (0.44) | DPP4KMT2AMAPK1LMNAMEN1 | |
| SCHEMBL13876111 | 0.85 | DPP4 (0.44) | DPP4KMT2AMAPK1LMNAMEN1 | |
| SCHEMBL13875834 | 0.85 | DPP4 (0.46) | DPP4LMNAALDH1A1L3MBTL1 | |
| SCHEMBL13875675 | 0.84 | DPP4 (0.45) | DPP4ALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL13866842 | 0.81 | DPP4 (0.61) | DPP4L3MBTL1 | |
| SCHEMBL13867030 | 0.81 | DPP4 (0.57) | DPP4KCNH2 | |
| SCHEMBL13866872 | 0.81 | DPP4 (0.46) | DPP4KMT2AALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL13866868 | 0.80 | DPP4 (0.49) | DPP4ALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL3872986 | 0.80 | DPP4 (0.41) | DPP4KMT2AMAPK1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |