Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866870 | 1.00 | DPP4 (0.44) | DPP4GAAALDH1A1MAPK1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL3872990 | 0.91 | DPP4 (0.41) | DPP4GAAALDH1A1MAPK1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL3872986 | 0.91 | DPP4 (0.41) | DPP4GAAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL13875834 | 0.86 | DPP4 (0.46) | DPP4ALDH1A1L3MBTL1LMNATSHR | |
| SCHEMBL13866869 | 0.85 | DPP4 (0.62) | DPP4ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL13875675 | 0.85 | DPP4 (0.45) | DPP4ALDH1A1L3MBTL1POLBSIRT5 | |
| SCHEMBL13866842 | 0.82 | DPP4 (0.61) | DPP4L3MBTL1FAP | |
| SCHEMBL13866872 | 0.81 | DPP4 (0.46) | DPP4ALDH1A1L3MBTL1HPGDHSD17B10 | |
| SCHEMBL13866868 | 0.81 | DPP4 (0.49) | DPP4ALDH1A1L3MBTL1POLBSIRT5 | |
| SCHEMBL13866871 | 0.80 | DPP4 (0.64) | DPP4ALDH1A1MAPK1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |