SCHEMBL13866879

SCHEMBL13866879

CC#CCn1c(=O)n(C)c2nc(Cl)nc(N3CCCC(NC)C3)c21

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.48
CHRM1 P11229 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3879683 0.92 DPP4 (0.43) DPP4CHRM1
SCHEMBL13866878 0.86 DPP4 (0.65) DPP4CHRM1
SCHEMBL13866877 0.84 DPP4 (0.59) DPP4
Trifluoroacetic Acid SCHEMBL3881731 0.79 DPP4 (0.56) DPP4CHRM1
SCHEMBL13866842 0.77 DPP4 (0.61) DPP4
SCHEMBL3883157 0.75 DPP4 (0.43) DPP4CHRM1
SCHEMBL13876113 0.72 DOT1L (0.39) DPP4
SCHEMBL3887947 0.71 DPP4 (0.45) DPP4CHRM1
Trifluoroacetic Acid SCHEMBL3879690 0.70 DPP4 (0.52) DPP4
SCHEMBL13200727 0.69 DPP4 (0.52) DPP4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524847-B2 Fused 1,3-dihydro-imidazole ring compounds EISAI R&D MANAGEMENT CO., LTD. (JP) 2009-04-28 US disclosed