Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.38 |
| ▸ | FAP | Q12884 | 5/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3877567 | 0.95 | DPP4 (0.37) | DPP4FAPDPP9CHRM1 | |
| SCHEMBL13875757 | 0.90 | P2RX3 (0.36) | HTR3A | |
| SCHEMBL13866857 | 0.89 | DPP4 (0.49) | DPP4FAPDPP9CHRM1 | |
| SCHEMBL3877571 | 0.85 | DPP4 (0.37) | DPP4FAPDPP9HTR3ACHRM1 | |
| Trifluoroacetic Acid SCHEMBL3874825 | 0.84 | DPP4 (0.46) | DPP4FAPDPP9CHRM1 | |
| SCHEMBL13866918 | 0.81 | DPP4 (0.44) | DPP4FAPDPP9HTR3A | |
| SCHEMBL13866946 | 0.80 | DPP4 (0.43) | DPP4FAPDPP9HTR3ACHRM1 | |
| Trifluoroacetic Acid SCHEMBL3875531 | 0.78 | DPP4 (0.39) | DPP4FAPDPP9CHRM1 | |
| Trifluoroacetic Acid SCHEMBL3875625 | 0.77 | DPP4 (0.38) | DPP4FAPDPP9 | |
| SCHEMBL13867092 | 0.76 | DPP4 (0.42) | DPP4FAPDPP9CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |