Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.53 |
| ▸ | FAP | Q12884 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3875979 | 0.93 | DPP4 (0.47) | DPP4FAPALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL13866997 | 0.85 | DPP4 (0.45) | DPP4FAPDPP9ABCC1 | |
| SCHEMBL13866887 | 0.85 | DPP4 (0.56) | DPP4FAPALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL13867026 | 0.85 | DPP4 (0.56) | DPP4FAPDPP9 | |
| SCHEMBL13866963 | 0.84 | DPP4 (0.48) | DPP4FAPALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL13866993 | 0.81 | DPP4 (0.44) | DPP4FAPDPP9HTR3A | |
| SCHEMBL13867003 | 0.81 | DPP4 (0.44) | DPP4FAPDPP9 | |
| SCHEMBL13867007 | 0.81 | DPP4 (0.49) | DPP4FAPDPP9ABCC1 | |
| SCHEMBL13867042 | 0.81 | DPP4 (0.56) | DPP4FAPDPP9 | |
| SCHEMBL13867002 | 0.80 | DPP4 (0.43) | DPP4FAPDPP9ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |