Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.44 |
| ▸ | FAP | Q12884 | 6/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3874829 | 0.92 | DPP4 (0.38) | DPP4FAPHTR2CKCNH2DPP9 | |
| SCHEMBL13875892 | 0.87 | HTR2C (0.44) | HTR2C | |
| SCHEMBL13866993 | 0.86 | DPP4 (0.44) | DPP4FAPHTR2CDPP9 | |
| SCHEMBL13866997 | 0.85 | DPP4 (0.45) | DPP4FAPHTR2CDPP9 | |
| SCHEMBL13867026 | 0.85 | DPP4 (0.56) | DPP4FAPHTR2CDPP9 | |
| SCHEMBL13867002 | 0.83 | DPP4 (0.43) | DPP4FAPHTR2CDPP9 | |
| SCHEMBL13866893 | 0.83 | DPP4 (0.45) | DPP4FAPDPP9CHRM1 | |
| SCHEMBL13866922 | 0.81 | DPP4 (0.44) | DPP4FAPDPP9 | |
| SCHEMBL13867010 | 0.81 | DPP4 (0.53) | DPP4FAPDPP9 | |
| SCHEMBL13867007 | 0.80 | DPP4 (0.49) | DPP4FAPKCNH2DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |