Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | KDM5A | P29375 | 4/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10760746 | 0.93 | EPHX1 (0.71) | EPHX1KDM5APHF8KDM4CALDH1A1 | |
| SCHEMBL681370 | 0.92 | EPHX1 (0.55) | EPHX1KDM5APHF8KDM4CALDH1A1 | |
| SCHEMBL1206276 | 0.90 | EPHX1 (0.52) | EPHX1KDM5APHF8KDM4CALDH1A1 | |
| SCHEMBL16720923 | 0.89 | EPHX1 (0.48) | EPHX1KDM4CPRMT3CARM1PRMT6 | |
| SCHEMBL29286833 | 0.88 | EPHX1 (0.64) | EPHX1KDM5APHF8KDM4CALDH1A1 | |
| SCHEMBL29286807 | 0.88 | EPHX1 (0.64) | EPHX1KDM5APHF8KDM4CALDH1A1 | |
| SCHEMBL21949028 | 0.88 | EPHX1 (0.56) | EPHX1KDM5APHF8KDM4CPRMT3 | |
| SCHEMBL24065809 | 0.87 | EPHX1 (0.48) | EPHX1KDM5APHF8KDM4CALDH1A1 | |
| SCHEMBL681618 | 0.87 | EPHX1 (0.48) | EPHX1KDM5APHF8KDM4CALDH1A1 | |
| SCHEMBL13867483 | 0.87 | EPHX1 (0.46) | EPHX1KDM4CPRMT3CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517913-B2 | Polyamine conjugates with acidic retinoids and preparation thereof | PAPAIOANNOU DIONYSIOS | 2009-04-14 | — | — | US | disclosed |