Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13867703 | 1.00 | NR1H2 (0.39) | NR1H2BTKALDH1A1HPGDALOX5AP | |
| SCHEMBL15194967 | 1.00 | NR1H2 (0.39) | NR1H2BTKALDH1A1HPGDALOX5AP | |
| SCHEMBL13864820 | 0.88 | BTK (0.33) | NR1H2BTKALDH1A1HPGDALOX5AP | |
| SCHEMBL13408415 | 0.88 | NR1H2 (0.46) | NR1H2 | |
| SCHEMBL20129230 | 0.88 | LMNA (0.35) | NR1H2BTKALDH1A1HPGDALOX5AP | |
| SCHEMBL15194959 | 0.87 | BTK (0.32) | NR1H2BTKALOX5APFEN1 | |
| SCHEMBL14281492 | 0.86 | BTK (0.31) | BTK | |
| SCHEMBL2375376 | 0.84 | NR1H2 (0.43) | NR1H2 | |
| SCHEMBL2375379 | 0.84 | NR1H2 (0.43) | NR1H2 | |
| SCHEMBL20335266 | 0.84 | NR1H2 (0.43) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538131-B2 | 2-{-3-′2-(phenyl)-oxazol-4-ylmethoxymethyl-cyclohexylmethoxy}-propionic acid derivatives useful as peroxisome proliferator-activated receptor (PPAR) ligands for the treatment of hyperlipidemia and diabetes | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-05-26 | — | — | US | disclosed |