Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 3/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3906716 | 0.88 | PTPN1 (0.71) | PTPN1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL3911917 | 0.82 | PTPN1 (0.49) | PTPN1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL3906530 | 0.81 | PTPN1 (0.48) | PTPN1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL3908251 | 0.81 | PTPN1 (0.48) | PTPN1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL2682770 | 0.80 | MAPT (0.48) | PTPN1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL6278144 | 0.79 | PTPN1 (0.46) | PTPN1KMT2AMAPTTSHRGAA | |
| SCHEMBL3908457 | 0.79 | PTPN1 (0.46) | PTPN1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL3908464 | 0.79 | PTPN1 (0.46) | PTPN1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL3909688 | 0.79 | PTPN1 (0.46) | PTPN1KMT2AMAPTTSHRGAA | |
| SCHEMBL3906569 | 0.79 | ALDH1A1 (0.49) | PTPN1KMT2AMAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | disclosed |