Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.47 |
| ▸ | PTPRC | P08575 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CD69 | Q07108 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13877637 | 0.79 | PTPN1 (0.35) | PTPN1PTPN2PTPRC | |
| SCHEMBL3903644 | 0.77 | PTPN1 (0.71) | PTPN1PTPN2PTPRC | |
| SCHEMBL3907055 | 0.75 | PTPN1 (0.72) | PTPN1PTPN2PTPRC | |
| SCHEMBL3906241 | 0.74 | PTPN1 (0.55) | PTPN1PTPN2PTPRC | |
| SCHEMBL3915374 | 0.74 | PTPN1 (0.73) | PTPN1PTPN2PTPRC | |
| SCHEMBL3909642 | 0.74 | PTPN1 (0.56) | PTPN1PTPN2PTPRC | |
| SCHEMBL3914494 | 0.73 | PTPN1 (0.55) | PTPN1PTPN2PTPRC | |
| SCHEMBL3906322 | 0.73 | PTPN1 (0.73) | PTPN1PTPN2PTPRC | |
| SCHEMBL7424901 | 0.72 | KMT2A (0.57) | PTPN1KMT2ACD69KDM4E | |
| SCHEMBL3919822 | 0.72 | PTPN1 (0.56) | PTPN1PTPN2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250302815-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC | 2025-10-02 | — | — | US | disclosed |
| EP-4384512-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | Calico Life Sciences LLC (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250302815-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | PTPN1, PTPN2, PTPN18 | PTPN1 1/4885PTPN2 2/4885PTPRC 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.