Diethyl Maleate

Diethyl Maleate

SCHEMBL138683

CCOC(=O)/C=C/C(=O)OCC.[Zn]

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.76
ATM Q13315 1/20 0.54
MAPT P10636 4/20 0.54
NPSR1 Q6W5P4 1/20 0.52
ALDH1A1 P00352 3/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
LMNA P02545 2/20 0.48
HSD17B10 Q99714 1/20 0.48
MDM2 Q00987 1/20 0.47
ALOX15 P16050 1/20 0.46
TTR P02766 1/20 0.46
DPP4 P27487 1/20 0.46
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethyl Maleate SCHEMBL28380879 1.00 HCAR2 (0.76) HCAR2ATMMAPTNPSR1ALDH1A1
Diethyl Maleate SCHEMBL28244169 1.00 HCAR2 (0.76) HCAR2ATMMAPTNPSR1ALDH1A1
Diethyl Maleate SCHEMBL27966383 0.97 HCAR2 (0.80) HCAR2ATMMAPTNPSR1ALDH1A1
Diethyl Maleate SCHEMBL42602 0.97 HCAR2 (0.80) HCAR2ATMMAPTNPSR1ALDH1A1
Diethyl Maleate SCHEMBL60423 0.97 HCAR2 (0.80) HCAR2ATMMAPTNPSR1ALDH1A1
Diethyl Maleate SCHEMBL2015896 0.97 HCAR2 (0.80) HCAR2ATMMAPTNPSR1ALDH1A1
Diethyl Maleate SCHEMBL2015895 0.97 HCAR2 (0.80) HCAR2ATMMAPTNPSR1ALDH1A1
Diethyl Maleate SCHEMBL43033 0.97 HCAR2 (0.80) HCAR2ATMMAPTNPSR1ALDH1A1
Diethyl Maleate SCHEMBL8935022 0.94 HCAR2 (0.76) HCAR2ATMMAPTNPSR1ALDH1A1
Diethyl Maleate SCHEMBL135447 0.94 HCAR2 (0.76) HCAR2ATMMAPTNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4652222-A1 POLYSTYRENE FOAMS WITH A FLUOROPOLYMER ADDITIVE, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2025-11-26 EP claimed
WO-2024176037-A1 POLYSTYRENE FOAMS WITH A FLUOROPOLYMER ADDITIVE, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-08-29 WO claimed
EP-4421114-A1 HIGH FLOW POLYSTYRENE RESINS, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2024-08-28 EP claimed
EP-4421115-A1 POLYSTYRENE FOAMS WITH A FLUOROPOLYMER ADDITIVE, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2024-08-28 EP claimed
CN-106232881-B Polymer foam 弗纳技术股份有限公司 2020-12-08 CN claimed
US-10745537-B2 Polymer foams FINA TECHNOLOGY, INC. (US) 2020-08-18 US claimed
US-10619014-B2 Masterbatch formulation and formation FINA TECHNOLOGY, INC. (US) 2020-04-14 US claimed
CN-109071943-A Production of processing aids 弗纳技术股份有限公司 2018-12-21 CN claimed
EP-3322737-A1 POLYMER FOAMS Fina Technology, Inc. (US) 2018-05-23 EP claimed
US-20180002495-A1 Masterbatch Formulation and Formation FINA TECHNOLOGY, INC. 2018-01-04 US claimed
US-20090275716-A1 Branched Ionomers FINA TECHNOLOGY,INC. (US) 2009-11-05 US claimed
US-7601788-B2 Branched ionomers FINA TECHNOLOGY, INC. (US) 2009-10-13 US claimed
US-20080051540-A1 BRANCHED IONOMERS FINA TECHNOLOGY, INC. (US) 2008-02-28 US claimed
CN-101107278-A Branched ionomers FINA TECHNOLOGY (US) 2008-01-16 CN claimed
US-7309749-B2 Copolymerizing monomer having an aromatic moiety (styrene) and an unsaturated alkyl moiety and a second monomer having an ionic moiety and at least one unsaturated moiety (sodium methacrylate and zinc dimethacrylate; can be foamed; high temperature performance such as for microwave safe dishes, utensils FINA TECHNOLOGY, INC. (US) 2007-12-18 US claimed
EP-1841801-A2 BRANCHED IONOMERS FINA TECHNOLOGY, INC. (US) 2007-10-10 EP claimed
US-20070191536-A1 Branched ionomers FINA TECHNOLOGY, INC. (US) 2007-08-16 US claimed
US-7179873-B2 Branched ionomers FINA TECHNOLOGY, INC. (US) 2007-02-20 US claimed
WO-2006081295-A2 BRANCHED IONOMERS FINA TECHNOLOGY, INC. (US) 2006-08-03 WO claimed
US-20060167149-A1 Branched ionomers FINA TECHNOLOGY, INC. (US) 2006-07-27 US claimed