SCHEMBL13868945

SCHEMBL13868945

NC(=O)CN1C=NC(C=O)C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28886735 0.61
SCHEMBL480879 0.58 KDM4E (0.31)
SCHEMBL9048947 0.58 KDM4E (0.31)
SCHEMBL13693832 0.57 KDM4E (0.41) APEX1BLM
Hydrochloric Acid SCHEMBL8005958 0.56
SCHEMBL2559463 0.56 KDM4E (0.48)
Bromide SCHEMBL3847723 0.56 APEX1 (0.34) APEX1BLM
SCHEMBL15196537 0.56 RAB9A (0.33)
SCHEMBL4957090 0.55 TSHR (0.35) APEX1BLM
SCHEMBL7962189 0.55 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7531542-B2 Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor WYETH (US) 2009-05-12 US disclosed