Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869839 | 0.88 | KDM4E (0.37) | PIM1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL13869640 | 0.87 | MAOB (0.44) | PIM1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL13869476 | 0.86 | KDM4E (0.37) | PIM1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL13869237 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869284 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869388 | 0.83 | GPR55 (0.45) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869319 | 0.83 | MAOB (0.42) | PIM1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL13869428 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869409 | 0.80 | MAPT (0.39) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL13869345 | 0.80 | KDM4E (0.37) | KDM4EALDH1A1MAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |