Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869478 | 0.76 | KDM4E (0.54) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL13869460 | 0.74 | KDM4E (0.56) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL13869816 | 0.74 | KDM4E (0.56) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL13869429 | 0.74 | CYP1A2 (0.58) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL13869810 | 0.74 | MEN1 (0.34) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL13869472 | 0.71 | ALDH1A1 (0.41) | MAOBALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL13869656 | 0.70 | MAOB (0.41) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL13869496 | 0.69 | ALDH1A1 (0.42) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL13869841 | 0.69 | KDM4E (0.54) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL13869474 | 0.69 | MAPT (0.59) | MAOBALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |