Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.75 |
| ▸ | MAPT | P10636 | 14/20 | 0.57 |
| ▸ | MEN1 | O00255 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921021 | 0.89 | CYP19A1 (0.67) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869410 | 0.88 | CYP19A1 (0.77) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13886341 | 0.88 | CYP19A1 (0.77) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869563 | 0.87 | CYP19A1 (0.64) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869607 | 0.86 | CYP19A1 (0.62) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869596 | 0.85 | CYP19A1 (0.60) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869595 | 0.85 | CYP19A1 (0.60) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869425 | 0.83 | CYP19A1 (0.68) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL18113715 | 0.82 | MAPT (0.75) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29375109 | 0.82 | MAPT (0.75) | CYP19A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |