Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869720 | 0.93 | ALDH1A1 (0.33) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL13869787 | 0.90 | ALDH1A1 (0.35) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL13869632 | 0.87 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL13869585 | 0.83 | MAPT (0.34) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL13869816 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL13869656 | 0.74 | MAOB (0.41) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL13886434 | 0.74 | MEN1 (0.34) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL13869478 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL13869701 | 0.73 | KDM4E (0.39) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL13869810 | 0.73 | MEN1 (0.34) | KDM4EALDH1A1HPGDMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |