Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925516 | 0.89 | MEN1 (0.45) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL2917255 | 0.85 | MAPT (0.38) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL2918293 | 0.79 | MAPT (0.43) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL13869790 | 0.76 | HSD11B1 (0.52) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL13869793 | 0.75 | MAPT (0.44) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL2926746 | 0.74 | MEN1 (0.48) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL2925396 | 0.71 | MEN1 (0.42) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL2917261 | 0.71 | MAPT (0.43) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL2922001 | 0.70 | MAPT (0.41) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL2924591 | 0.70 | HSD11B1 (0.46) | MEN1KMT2ATDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524853-B2 | Compounds and their use in therapy | SOLVAY PHARMACEUTICALS B.V. (NL) | 2009-04-28 | — | — | US | disclosed |
| US-7524853-B2 | Compounds and their use in therapy | SOLVAY PHARMACEUTICALS B.V. (NL) | 2009-04-28 | — | — | US | disclosed |
| US-7465739-B2 | Compounds and their use in therapy | SOLVAY PHARMACEUTICALS B.V. (NL) | 2008-12-16 | — | — | US | disclosed |
| US-7465739-B2 | Compounds and their use in therapy | SOLVAY PHARMACEUTICALS B.V. (NL) | 2008-12-16 | — | — | US | disclosed |