Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869313 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL13869270 | 0.88 | MAOB (0.44) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL13870256 | 0.84 | KDM4E (0.57) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL13870230 | 0.83 | KDM4E (0.58) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL13870236 | 0.83 | KDM4E (0.58) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL13869238 | 0.82 | MAPT (0.51) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL13869282 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL13869288 | 0.81 | MAPT (0.53) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL13869378 | 0.79 | KDM4E (0.45) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL13869512 | 0.79 | MAPT (0.43) | ALDH1A1KDM4EMAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521567-B2 | Amine compound and uses thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-21 | — | — | US | disclosed |
| US-7521567-B2 | Amine compound and uses thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-21 | — | — | US | disclosed |