Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.63 |
| ▸ | ITGAV | P06756 | 5/20 | 0.63 |
| ▸ | MC4R | P32245 | 6/20 | 0.53 |
| ▸ | MC5R | P33032 | 6/20 | 0.53 |
| ▸ | MC3R | P41968 | 6/20 | 0.53 |
| ▸ | MC1R | Q01726 | 6/20 | 0.53 |
| ▸ | CTSG | P08311 | 2/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | GRB7 | Q14451 | 1/20 | 0.47 |
| ▸ | TSLP | Q969D9 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908265 | 1.00 | ITGB3 (0.63) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL13870357 | 1.00 | ITGB3 (0.63) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL13014846 | 0.96 | ITGB3 (0.58) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL14090937 | 0.96 | ITGB3 (0.64) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL12353635 | 0.95 | ITGB3 (0.57) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL11928877 | 0.95 | ITGB3 (0.64) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL11933451 | 0.94 | ITGB3 (0.57) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL16298655 | 0.94 | ITGB3 (0.55) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL22003475 | 0.94 | ITGB3 (0.55) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL9909400 | 0.94 | ITGB3 (0.55) | ITGB3ITGAVMC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521419-B2 | Peptide-based compounds | GE HEALTHCARE AS (NO) | 2009-04-21 | — | — | US | disclosed |