Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870536 | 0.91 | HRH1 (0.40) | HRH1HRH4 | |
| SCHEMBL13870569 | 0.87 | HRH1 (0.43) | HRH1HRH4 | |
| SCHEMBL31350805 | 0.79 | HRH1 (0.47) | HRH1HRH4 | |
| SCHEMBL8317130 | 0.79 | HRH1 (0.47) | HRH1HRH4 | |
| SCHEMBL13870558 | 0.78 | KCNH2 (0.46) | HRH1 | |
| SCHEMBL13870542 | 0.78 | HRH1 (0.52) | HRH1 | |
| Hydrochloric Acid SCHEMBL9718788 | 0.78 | HRH1 (0.46) | HRH1HRH4 | |
| SCHEMBL10373496 | 0.76 | ALDH1A1 (0.63) | — | |
| SCHEMBL13870560 | 0.76 | KCNH2 (0.54) | — | |
| SCHEMBL13870552 | 0.76 | KCNH2 (0.66) | HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524864-B2 | Methods of treating sleep disorders | HYPNION, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-7524864-B2 | Methods of treating sleep disorders | HYPNION, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-7482460-B2 | Doxepin analogs and methods of use thereof | HYPNION, INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-7482460-B2 | Doxepin analogs and methods of use thereof | HYPNION, INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-7411069-B2 | Doxepin analogs and methods of use thereof | HYPNION, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7411069-B2 | Doxepin analogs and methods of use thereof | HYPNION, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7355042-B2 | Treatment of CNS disorders using CNS target modulators | HYPNION, INC. (US) | 2008-04-08 | — | — | US | disclosed |
| US-7355042-B2 | Treatment of CNS disorders using CNS target modulators | HYPNION, INC. (US) | 2008-04-08 | — | — | US | disclosed |
| US-7326721-B2 | Doxepin analogs and methods of use thereof | HYPNION, INC. (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326721-B2 | Doxepin analogs and methods of use thereof | HYPNION, INC. (US) | 2008-02-05 | — | — | US | disclosed |
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7189757-B2 | Treatment of sleep disorders using CNS target modulators | HYPNION, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189757-B2 | Treatment of sleep disorders using CNS target modulators | HYPNION, INC. (US) | 2007-03-13 | — | — | US | disclosed |