Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.57 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3180354 | 1.00 | ATM (0.69) | ATMALDH1A1MAPTHPGDHTT | |
| SCHEMBL3180344 | 1.00 | ATM (0.69) | ATMALDH1A1MAPTHPGDHTT | |
| SCHEMBL13480903 | 1.00 | ATM (0.69) | ATMALDH1A1MAPTHPGDHTT | |
| SCHEMBL14345183 | 0.91 | ATM (0.81) | ATMALDH1A1MAPTHPGDHTT | |
| SCHEMBL5891287 | 0.82 | ATM (0.69) | ATMALDH1A1MAPTHPGDHTT | |
| SCHEMBL1104580 | 0.82 | ATM (0.69) | ATMALDH1A1MAPTHPGDHTT | |
| SCHEMBL1104574 | 0.81 | ATM (1.00) | ATMALDH1A1MAPTHPGDHTT | |
| SCHEMBL17616369 | 0.81 | ATM (0.67) | ATMALDH1A1MAPTHPGDHTT | |
| SCHEMBL13936105 | 0.81 | ATM (0.67) | ATMALDH1A1MAPTHPGDHTT | |
| SCHEMBL23823153 | 0.78 | ATM (0.63) | ATMALDH1A1MAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517904-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |