SCHEMBL1104574

SCHEMBL1104574

O=C1C2C3C=CC(O3)C2C(=O)N1c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 1.00
POLB P06746 1/20 0.58
ALDH1A1 P00352 7/20 0.56
CACNA1B Q00975 2/20 0.56
APBA1 Q02410 2/20 0.56
MAPT P10636 1/20 0.56
HPGD P15428 1/20 0.56
HTT P42858 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
GAA P10253 2/20 0.47
TSHR P16473 2/20 0.47
ALOX15 P16050 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PKM P14618 1/20 0.47
MAOA P21397 1/20 0.44
MAPK1 P28482 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14345183 0.90 ATM (0.81) ATMPOLBALDH1A1CACNA1BAPBA1
SCHEMBL3180354 0.81 ATM (0.69) ATMPOLBALDH1A1CACNA1BAPBA1
SCHEMBL13870645 0.81 ATM (0.69) ATMPOLBALDH1A1CACNA1BAPBA1
SCHEMBL3180344 0.81 ATM (0.69) ATMPOLBALDH1A1CACNA1BAPBA1
SCHEMBL1104580 0.81 ATM (0.69) ATMALDH1A1CACNA1BAPBA1MAPT
SCHEMBL5891287 0.81 ATM (0.69) ATMPOLBALDH1A1CACNA1BAPBA1
SCHEMBL13480903 0.81 ATM (0.69) ATMPOLBALDH1A1CACNA1BAPBA1
SCHEMBL18804483 0.81 MEN1 (0.72) ATMPOLBALDH1A1CACNA1BAPBA1
SCHEMBL13936105 0.80 ATM (0.67) ATMPOLBALDH1A1CACNA1BAPBA1
SCHEMBL17616369 0.80 ATM (0.67) ATMPOLBALDH1A1CACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8223472-B1 Norbornylene-based polymer systems for dielectric applications SANDIA CORPORATION (US) 2012-07-17 US claimed
US-3954913-A THERMAL DISCOLORATION INHIBITION THE STANDARD OIL COMPANY (US) 1976-05-04 US claimed
EP-2977098-B1 A POROUS MEMBRANE PREPARED FROM A SELF-ASSEMBLING BLOCK-COPOLYMER AS WELL AS A METHOD FOR MAKING SAME PALL CORP (US) 2018-07-18 EP disclosed
US-9856353-B2 Optical film and display device including same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-01-02 US disclosed
US-9616395-B2 Membrane comprising self-assembled block copolymer and process for producing the same by spray coating (Ic) Pall Corportaion (US) 2017-04-11 US disclosed
US-9604181-B2 Membrane comprising self-assembled block copolymer and process for producing the same by spray coating (IIc) PALL CORPORATION (US) 2017-03-28 US disclosed
US-9604181-B2 Membrane comprising self-assembled block copolymer and process for producing the same by spray coating (IIc) PALL CORPORATION (US) 2017-03-28 US disclosed
US-9593218-B2 Self-assembled structure and membrane comprising block copolymer and process for producing the same by spin coating (IIIa) PALL CORPORATION (US) 2017-03-14 US disclosed
US-9592476-B2 Membrane comprising self-assembled block copolymer and process for producing the same by hybrid casting (IIb) PALL CORPORATION (US) 2017-03-14 US disclosed
US-9592476-B2 Membrane comprising self-assembled block copolymer and process for producing the same by hybrid casting (IIb) PALL CORPORATION (US) 2017-03-14 US disclosed
US-9593219-B2 Membrane comprising self-assembled block copolymer and process for producing the same by spin coating (IIa) PALL CORPORATION (US) 2017-03-14 US disclosed
US-20090131682-A1 SUPPORTS FOR OLIGOMER SYNTHESIS ISIS PHARMACEUTICALS, INC. (US) 2009-05-21 US disclosed
US-7378533-B1 Method for preparing thermally cleavable surfactants without deprotonation SANDIA CORPORATION (US) 2008-05-27 US disclosed
US-7351837-B1 Thermally cleavable surfactants without deprotonation SANDIA CORPORATION (US) 2008-04-01 US disclosed
US-20080021224-A1 SUPPORTS FOR OLIGOMER SYNTHESIS ISIS PHARMACEUTICALS, INC. (US) 2008-01-24 US disclosed
US-20080021224-A1 SUPPORTS FOR OLIGOMER SYNTHESIS ISIS PHARMACEUTICALS, INC. (US) 2008-01-24 US disclosed
US-7202264-B2 Supports such as glass and styrene polymers functionalized with tricyclic hetercyclic anhydrides and imides, used in the preparation of oligonucleotides ISIS PHARMACEUTICALS, INC. (US) 2007-04-10 US disclosed
US-7202264-B2 Supports such as glass and styrene polymers functionalized with tricyclic hetercyclic anhydrides and imides, used in the preparation of oligonucleotides ISIS PHARMACEUTICALS, INC. (US) 2007-04-10 US disclosed
US-20040152905-A1 Universal building blocks and support media for synthesis of oligonucleotides and their analogs ISIS PHARMACEUTICALS, INC. 2004-08-05 US disclosed
US-3954913-A THERMAL DISCOLORATION INHIBITION THE STANDARD OIL COMPANY (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131682-A1 SUPPORTS FOR OLIGOMER SYNTHESIS ILK, NOP2, PFAS ATM 3498/4885POLB 512/4885ALDH1A1 4121/4885
US-20080021224-A1 SUPPORTS FOR OLIGOMER SYNTHESIS ILK, NOP2, PFAS ATM 3498/4885POLB 512/4885ALDH1A1 4121/4885
US-20040152905-A1 Universal building blocks and support media for synthesis of oligonucleotides and their analogs POLM, POLRMT, POLB ATM 2948/4885POLB 3/4885ALDH1A1 4408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.