Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | RPA1 | P27694 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CCR8 | P51685 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14484939 | 0.86 | MEN1 (0.76) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL13870885 | 0.82 | KMT2A (0.70) | MEN1KMT2ATP53ALDH1A1CCR8 | |
| SCHEMBL19667044 | 0.81 | MEN1 (0.67) | MEN1KMT2ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL15920271 | 0.80 | MEN1 (0.67) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL15920274 | 0.80 | MEN1 (0.66) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL1094889 | 0.79 | TP53 (1.00) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL13870901 | 0.79 | TP53 (1.00) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL17479368 | 0.79 | MEN1 (0.65) | MEN1KMT2ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL6357975 | 0.78 | MEN1 (0.64) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL15919998 | 0.77 | KMT2A (0.63) | MEN1KMT2ATP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | NR1H2, NR1H3, HRH2 | MEN1 2859/4885KMT2A 2570/4885TP53 4629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.