Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920275 | 0.81 | ALDH1A1 (0.63) | MEN1KMT2AKDM4ENPSR1ALDH1A1 | |
| SCHEMBL13870904 | 0.80 | MEN1 (1.00) | MEN1KMT2ATP53KDM4ETSHR | |
| SCHEMBL15920271 | 0.78 | MEN1 (0.67) | MEN1KMT2ATP53KDM4ETSHR | |
| SCHEMBL14484939 | 0.78 | MEN1 (0.76) | MEN1KMT2ATP53KDM4ENPSR1 | |
| SCHEMBL17479368 | 0.73 | MEN1 (0.65) | MEN1KMT2ATP53TSHRCNR2 | |
| SCHEMBL2740023 | 0.72 | KMT2A (0.64) | MEN1KMT2AKDM4ENPSR1ALDH1A1 | |
| SCHEMBL19667044 | 0.71 | MEN1 (0.67) | MEN1KMT2ATP53TSHRCNR2 | |
| SCHEMBL15919998 | 0.70 | KMT2A (0.63) | MEN1KMT2ATP53KDM4ENPSR1 | |
| SCHEMBL15612860 | 0.69 | TP53 (0.67) | MEN1KMT2ATP53ALDH1A1CCR8 | |
| SCHEMBL27632955 | 0.68 | MAPK14 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |