Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | ALB | P02768 | 5/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | PPARG | P37231 | 1/20 | 0.74 |
| ▸ | PPARD | Q03181 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | IL1RN | P18510 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TNF | P01375 | 1/20 | 0.62 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870931 | 0.99 | TP53 (0.98) | TP53ALBALDH1A1MAPTPPARG | |
| SCHEMBL13870890 | 0.90 | ALB (1.00) | TP53ALBALDH1A1PPARGPPARD | |
| SCHEMBL6357153 | 0.87 | ALB (0.83) | TP53ALBALDH1A1MAPTPPARG | |
| SCHEMBL17479208 | 0.86 | TP53 (0.75) | TP53ALBALDH1A1MAPTPPARG | |
| SCHEMBL21067755 | 0.85 | PPARG (1.00) | TP53ALBPPARGPPARDMEN1 | |
| SCHEMBL17479094 | 0.85 | MEN1 (0.79) | TP53ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1001462 | 0.85 | TP53 (0.73) | TP53ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL15276769 | 0.84 | ALDH1A1 (0.97) | TP53ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6359330 | 0.84 | TP53 (0.72) | TP53ALBALDH1A1MAPTPPARG | |
| SCHEMBL15076663 | 0.84 | TP53 (0.72) | TP53ALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | NR1H2, NR1H3, HRH2 | TP53 4629/4885ALB 3957/4885ALDH1A1 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.