Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.98 |
| ▸ | MEN1 | O00255 | 7/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870898 | 0.99 | MEN1 (1.00) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17109121 | 0.85 | ENPP2 (0.79) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13870923 | 0.84 | KMT2A (0.98) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13870919 | 0.83 | KMT2A (1.00) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4760580 | 0.81 | MEN1 (0.97) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4716208 | 0.80 | MEN1 (1.00) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4716285 | 0.80 | MEN1 (1.00) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4761472 | 0.79 | MEN1 (0.91) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13870901 | 0.77 | TP53 (1.00) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL1094889 | 0.77 | TP53 (1.00) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | NR1H2, NR1H3, HRH2 | KMT2A 2570/4885MEN1 2859/4885ALDH1A1 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.