Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.56 |
| ▸ | CNR1 | P21554 | 9/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2715695 | 0.91 | CNR2 (0.50) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL2715683 | 0.91 | CNR2 (0.57) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL13871490 | 0.91 | CNR2 (0.57) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL2715958 | 0.91 | CNR2 (0.54) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL2714870 | 0.89 | CNR2 (0.57) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL13871311 | 0.89 | CNR2 (0.48) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL13871314 | 0.87 | CNR2 (0.58) | CNR2CNR1TAS1R3TAS1R1DHODH | |
| SCHEMBL13871439 | 0.87 | CNR2 (0.48) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL14003103 | 0.86 | CNR2 (0.49) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL13871536 | 0.85 | CNR2 (0.46) | CNR2CNR1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099143-A1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | LAGU BHARAT | 2009-04-16 | — | — | US | disclosed |
| US-20090099143-A1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | LAGU BHARAT | 2009-04-16 | — | — | US | disclosed |
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099143-A1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | CNR2, CNR1, GPR18 | CNR2 1/4885CNR1 2/4885TAS1R3 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.