Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 20/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.41 |
| ▸ | KIT | P10721 | 3/20 | 0.41 |
| ▸ | FLT3 | P36888 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1652127 | 0.93 | PDGFRB (0.47) | PDGFRBPDGFRAKITFLT3 | |
| SCHEMBL1386717 | 0.86 | F10 (0.38) | PDGFRBPDGFRAKITFLT3 | |
| SCHEMBL4387290 | 0.86 | F10 (0.39) | — | |
| SCHEMBL4387303 | 0.86 | F10 (0.39) | — | |
| SCHEMBL1652705 | 0.85 | F10 (0.37) | PDGFRBPDGFRA | |
| SCHEMBL1652300 | 0.84 | PDGFRB (0.47) | PDGFRBPDGFRAKITFLT3 | |
| SCHEMBL27591331 | 0.82 | KCNH2 (0.37) | — | |
| SCHEMBL1652298 | 0.82 | PDGFRB (0.47) | PDGFRBPDGFRAKITFLT3 | |
| SCHEMBL28941456 | 0.80 | APP (0.34) | — | |
| SCHEMBL7146946 | 0.78 | F10 (0.44) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4829449-B2 | — | — | 2011-12-07 | — | — | JP | claimed |