Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | TARS1 | P26639 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146953 | 1.00 | F10 (0.44) | F10AKT1TARS1HSP90AB1ENPP1 | |
| SCHEMBL1384484 | 0.85 | F10 (0.45) | F10AKT1 | |
| SCHEMBL4387303 | 0.84 | F10 (0.39) | F10AKT1 | |
| SCHEMBL4387598 | 0.79 | F10 (0.63) | F10 | |
| SCHEMBL27591331 | 0.78 | KCNH2 (0.37) | F10 | |
| SCHEMBL1387133 | 0.78 | PDGFRB (0.42) | KIT | |
| SCHEMBL1652127 | 0.78 | PDGFRB (0.47) | F10KIT | |
| SCHEMBL1386139 | 0.77 | F10 (0.45) | F10 | |
| SCHEMBL1652705 | 0.76 | F10 (0.37) | F10AKT1 | |
| SCHEMBL28941456 | 0.76 | APP (0.34) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |