Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | CCR3 | P51677 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13873126 | 0.87 | EPHX2 (0.54) | EPHX2HRH1CCR3CYP2C9SMN1; SMN2 | |
| SCHEMBL13873213 | 0.86 | EPHX2 (0.60) | EPHX2CYP2C9CYP2J2SMN1; SMN2LMNA | |
| SCHEMBL13873129 | 0.86 | HRH1 (0.57) | EPHX2HRH1CCR3SMN1; SMN2KCNH2 | |
| SCHEMBL13873194 | 0.86 | EPHX2 (0.60) | EPHX2CYP2C9CYP2J2SMN1; SMN2LMNA | |
| SCHEMBL13873132 | 0.85 | EPHX2 (0.61) | EPHX2CYP2C9CYP2J2SMN1; SMN2LMNA | |
| SCHEMBL13873248 | 0.84 | EPHX2 (0.58) | EPHX2CYP2C9CYP2J2SMN1; SMN2LMNA | |
| SCHEMBL13873190 | 0.84 | EPHX2 (0.58) | EPHX2SMN1; SMN2LMNA | |
| SCHEMBL13873182 | 0.84 | GPR119 (0.64) | EPHX2HRH1CCR3SMN1; SMN2LMNA | |
| SCHEMBL13873173 | 0.84 | GPR119 (0.64) | EPHX2SMN1; SMN2LMNA | |
| SCHEMBL1809304 | 0.83 | HRH3 (0.53) | EPHX2LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | EPHX1, EPHX2, NCEH1 | EPHX2 2/4885HRH1 204/4885CCR3 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.