SCHEMBL13873451

SCHEMBL13873451

CC(=O)C(CN1C(=O)c2ccccc2C1=O)C(C)=O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
CA12 O43570 1/20 0.52
CA9 Q16790 1/20 0.52
KMT2A Q03164 3/20 0.48
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
PKM P14618 1/20 0.46
MAPK1 P28482 1/20 0.45
ELANE P08246 1/20 0.45
KDM4E B2RXH2 1/20 0.45
RAB9A P51151 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29740350 0.93 CA12 (0.53) ALDH1A1CA12CA9KMT2AMEN1
SCHEMBL8431420 0.93 CA12 (0.53) ALDH1A1CA12CA9KMT2AMEN1
SCHEMBL5998010 0.89 ALDH1A1 (0.49) ALDH1A1CA12CA9KMT2AMAPT
SCHEMBL5998387 0.87 ALDH1A1 (0.49) ALDH1A1KMT2AMAPTMEN1
SCHEMBL9386761 0.85 ALDH1A1 (0.56) ALDH1A1CA12CA9KMT2AMAPT
SCHEMBL9456474 0.84 ALDH1A1 (0.54) ALDH1A1CA12CA9KMT2AMAPT
SCHEMBL4410547 0.84 ALDH1A1 (0.54) ALDH1A1CA12CA9KMT2AMAPT
SCHEMBL8574998 0.83 MAPK1 (0.56) ALDH1A1CA12CA9KMT2AMAPT
SCHEMBL5997212 0.82 NPSR1 (0.60) ALDH1A1CA12CA9KMT2AMAPT
SCHEMBL13873450 0.80 ALDH1A1 (0.54) ALDH1A1CA12CA9KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090104671-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE 2-(N-SUBSTITUTED AMINOMETHYL)-3-HYDROXYBUTYRIC ACID ESTER KANEKA CORPORATION (JP) 2009-04-23 US disclosed