Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13873648 | 0.89 | HRH3 (0.57) | CYP2C9EPHX2CYP2J2HRH3PDE4B | |
| SCHEMBL13873620 | 0.82 | EPHX2 (0.61) | CYP2C9EPHX2CYP2J2HRH3SMN1; SMN2 | |
| SCHEMBL13873841 | 0.79 | EPHX2 (0.68) | CYP2C9EPHX2CYP2J2PDE4BMAPK14 | |
| SCHEMBL13873671 | 0.79 | CYP2C9 (0.57) | CYP2C9EPHX2CYP2J2HRH3PDE4B | |
| SCHEMBL13873845 | 0.78 | EPHX2 (0.61) | CYP2C9EPHX2CYP2J2PDE4BSMN1; SMN2 | |
| SCHEMBL13873609 | 0.78 | MEN1 (0.56) | CYP2C9HRH3LMNACYP3A4HTT | |
| SCHEMBL13873842 | 0.78 | ALDH1A1 (0.54) | CYP2C9EPHX2CYP2J2SMN1; SMN2LMNA | |
| SCHEMBL13873852 | 0.78 | CYP2C9 (0.66) | CYP2C9EPHX2CYP2J2PDE4BSMN1; SMN2 | |
| SCHEMBL13873851 | 0.78 | EPHX2 (0.53) | CYP2C9EPHX2CYP2J2PDE4BSMN1; SMN2 | |
| SCHEMBL13873636 | 0.77 | MEN1 (0.61) | HRH3SMN1; SMN2MMP13GLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | US | disclosed |
| WO-2007106705-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | EPHX1, EPHX2, NCEH1 | CYP2C9 477/4885EPHX2 2/4885CYP2J2 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.