Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 18/20 | 0.86 |
| ▸ | PPP3CA | Q08209 | 10/20 | 0.86 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113032 | 0.97 | FKBP1A (0.90) | FKBP1APPP3CAMEN1LMNAMAPT | |
| SCHEMBL1387304 | 0.96 | FKBP1A (0.84) | FKBP1APPP3CAMEN1LMNAMAPT | |
| SCHEMBL1387458 | 0.95 | FKBP1A (0.93) | FKBP1APPP3CAMEN1LMNAMAPT | |
| SCHEMBL9110476 | 0.95 | FKBP1A (0.93) | FKBP1APPP3CAMEN1LMNAMAPT | |
| SCHEMBL1387525 | 0.94 | FKBP1A (0.86) | FKBP1APPP3CAMEN1LMNAMAPT | |
| SCHEMBL1387502 | 0.94 | FKBP1A (0.86) | FKBP1APPP3CAMEN1LMNAMAPT | |
| SCHEMBL9111906 | 0.94 | FKBP1A (0.86) | FKBP1APPP3CAMEN1LMNAMAPT | |
| SCHEMBL9108234 | 0.94 | FKBP1A (0.86) | FKBP1APPP3CAMEN1LMNAMAPT | |
| SCHEMBL1387388 | 0.93 | FKBP1A (0.88) | FKBP1APPP3CAMEN1LMNAMAPT | |
| SCHEMBL9111999 | 0.93 | FKBP1A (0.89) | FKBP1APPP3CAMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H09503507-A | — | — | 1997-04-08 | — | — | JP | claimed |
| WO-1995009857-A1 | O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | claimed |