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Sugi Predict / Compounds / SCHEMBL1387498

SCHEMBL1387498

SCHEMBL1387498

C[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1C(=O)N2C(C(=O)OC(C)(C)C)=C(CO)S[C@H]12

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 19/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25601297 0.91 ELANE (0.38) ELANE
SCHEMBL25601304 0.91 ELANE (0.38) ELANE
SCHEMBL8133240 0.88 ELANE (0.40) ELANE
SCHEMBL7831926 0.88 ELANE (0.40) ELANE
SCHEMBL25601308 0.88 ELANE (0.45) ELANE
SCHEMBL10668491 0.86 ELANE (0.40) ELANE
SCHEMBL25601307 0.86 ELANE (0.35) ELANE
SCHEMBL1388898 0.85 ELANE (0.39) ELANE
SCHEMBL22844537 0.85 ELANE (0.39) ELANE
SCHEMBL25601234 0.85 ELANE (0.39) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-H10503521-A — — 1998-03-31 — — JP claimed
EP-0606336-B1 PROCESS FOR MAKING ANTIMICROBIAL QUINOLONYL LACTAMS PROCTER & GAMBLE PHARMA (US) 1997-03-19 — — EP claimed
WO-1996004286-A1 PROCESS FOR MAKING QUINOLONYL LACTAM ANTIMICROBIALS AND NOVEL INTERMEDIATE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1996-02-15 — — WO claimed
WO-1993007154-A1 PROCESS FOR MAKING ANTIMICROBIAL QUINOLONYL LACTAMS PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1993-04-15 — — WO claimed
EP-0606336-B1 PROCESS FOR MAKING ANTIMICROBIAL QUINOLONYL LACTAMS PROCTER & GAMBLE PHARMA (US) 1997-03-19 — — EP disclosed